I have one of these
Dog Crates | Dog Cages | TransK9USA | Acura | MDX which are designed to fit your specific vehicle. I have the one that fits the Toyota Highlander, which has a removable center divider that I don't use, as both dogs travel in there together with no issues. Yeah they are a bit pricey, and shipping will be about $350. I first saw these when I was at Crufts a few years ago and was really impressed with the quality. I really like that I can lock them to make sure the dogs are secure. The other nice thing is I can leave my back seats up and still use the kennel, which wasn't an option with other types of crates.
I looked at other types of kennels and dividers and in the end I felt it was worth spending the money as it was something that I use pretty much every day going to different training areas for field work and obedience. I felt this was probably the safest option.